Wednesday, January 13, 2010

Keeping Depression at Bay Naturally Part 2...5-HTP

This is information taken from The Progressive Health Site about the risks and benefits if taking 5 HTP for depression and other health issues

5-HTP is a supplement used to help with many conditions, including depression, obesity, carbohydrate craving, bulimia, insomnia, narcolepsy, sleep apnea, migraine, headaches, and fibromyalgia.

Although there are several conditions, which are helped by, taking 5-HTP there are also dangers when taking it with out know how to take it.

Benefits of Taking 5-HTP

5-HTP is an amino acid. The body makes 5-HTP from tryptophan (an essential amino acid) and converts it to an important brain chemical known as serotonin.

Tryptophan and 5-HTP dietary supplements help raise serotonin levels in the brain, which may have a positive effect on sleep, mood, anxiety, aggression, appetite, temperature, sexual behavior, and pain sensation.

  • Depression - Low levels of serotonin in the brain can contribute to the development of depression. Many drugs prescribed for depression increase serotonin levels. Some studies indicate that 5-HTP may be as effective as certain antidepressant drugs in treating individuals with mild to moderate depression.

    Such individuals have shown improvements in mood, anxiety, insomnia, and physical symptoms.
  • Fibromyalgia - 5-HTP has been shown to improve sleep quality and reduce pain, stiffness, anxiety, and depression in individuals with fibromyalgia.
  • Insomnia - Medical research indicates that supplementation with tryptophan before bedtime can induce sleepiness and delay wake times. Studies also suggest that 5-HTP may be useful in treating insomnia associated with depression.
  • Headaches - Some studies suggest that 5-HTP may be effective in children and adults with various types of headaches including migraines.
  • Obesity - There is some evidence that low tryptophan levels may contribute to excess fat and carbohydrate intake.

When Not To Take 5-HTP

As with any supplement, 5-HTP can be abused. However, when used wisely, it has proven itself to be a safe and effective supplement.

While this supplement appears to be safe for most people, 5-HTP danger occurs when people mix 5-HTP with prescription medications and herbal supplements. Taking too much 5-HTP is also dangerous.

  • 5-HTP should not be taken concurrently with anti- depressants except under the supervision of a physician, because 5-HTP increases the activity of these drugs. Mixing SSRI medications and 5-HTP may result in a rare but extremely serious condition called serotonin syndrome. People with serotonin syndrome exhibit a variety of symptoms including confusion, restlessness, hallucinations, fever, nausea, and vomiting. Coma and death follow swiftly after symptoms appear.
  • 5-HTP should be avoided by pregnant women, nursing mothers and those with significant cardiovascular disease.
  • It is also contraindicated in those with carcinoid tumors.
  • Mixing 5 HTP with herbal supplements for depression such as St. John's Wort is also not recommended. Like SSRI medications, St. John's Wort alters the delicate balance of brain chemistry. 5 HTP can tip the balance into dangerous territory.

5-HTP Overdose

Individuals who take 5-HTP may expect it to act quickly, altering their mood overnight. Medications, supplements and herbs that act upon neurotransmitters usually need to be taken for several weeks before patients start to feel the effects.

Some people take more and more 5 HTP, hoping that taking more will increase the effectiveness more quickly. This can create a dangerous condition called, serotonin syndrome. Many alternate health practitioners recommend starting slowly with 5 HTP and taking it for only short periods of time to avoid dangerous overdoses.

5-HTP Side Effects

Reported side effects from taking 5-HTP include nausea, vomiting, and difficulty breathing. Dangerous doses of 5-HTP can cause agitation, fast heart rate, a boost in blood pressure—and in rare cases, coma and even death.

Combining it with an antidepressant, any other drug that affects serotonin levels or herbal supplements like St. John's Wort can also cause such side effects. People who have heart disease, peptic ulcers, kidney disease, or clotting disorders should definitely not take this supplement.

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